C5AR1 Antibody

Size : 50 µg Clone Number: Aliases: ANAPHYLATOXIN RECEPTOR antibody; C5a anaphylatoxin chemotactic receptor antibody; C5a anaphylatoxin receptor antibody; C5A antibody; C5a ligand antibody; C5a-R antibody; C5aR antibody; C5AR_HUMAN antibody; c5ar1 antibody; C5R1 antibody; CD88 antibody; CD88 antigen antibody; Complement component 5 receptor 1 antibody; Complement component 5 receptor 2 antibody; Complement component 5a receptor 1 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P21730 Immunogen: Recombinant Human C5a anaphylatoxin chemotactic receptor 1 protein (1-36AA) Host: Rabbit Reactivity: Human Tested Applications: ELISA, WB, IF; Recommended dilution: WB: 1: 1000-1: 5000, IF: 1: 50-1: 200 Background: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed: 1847994, PubMed: 8182049, PubMed: 7622471, PubMed: 9553099, PubMed: 10636859, PubMed: 15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed: 8182049, PubMed: 7622471, PubMed: 9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed: 10636859, PubMed: 15153520). Clonality: Polyclonal Isotype: IgG Purification Method: 95%, Protein G purified Conjugate: Non-conjugated Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: C5AR1 Research Areas: Cancer; Immunology; Metabolism; Signal transduction